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Sports Updates > News > Baseball > Fantasy baseball lineup advice for Wednesday: Ashcraft, Holmes among top streamers
Baseball

Fantasy baseball lineup advice for Wednesday: Ashcraft, Holmes among top streamers

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Last updated: April 22, 2026 3:02 am
Published April 22, 2026
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Check out all of our starting pitcher rankings and other lineup selection tools here to help you make smart lineup decisions. All fantasy advice is geared toward ESPN 10-team leagues with .

Note: All information is accurate as of the time of publication. For updates, as well as any breaking news that might impact today’s MLB slate, be sure to check out the latest .

Other resources: |
| Betting notes for Wednesday

is one of the few bright spots for the so far this season. Granted, he hasn’t pitched as well as his 1.96 ERA and 1.09 WHIP indicate, but his 4.06 xFIP and 4.26 SIERA are below league average and worthy of streaming for favorable matchups. The are in Queens for an interleague set, and not only is Citi Field one of the top pitching venues in the league, but the early evening forecast also calls for chilly temperatures and the wind blowing in.

The weather won’t be a factor in Arlington when the and square off in Globe Life Field with the retractable roof closed; however, the venue traditionally favors pitching, and Pirates’ righty has begun the season with 27 strikeouts in 22 2/3 innings, with just seven walks and no homers allowed. Through Monday’s action, the Rangers played only six home games, but they hit just two home runs in those contests.

With Great American Ball Park as their home field, it makes sense for the to perform worse on the road, but they have the third-lowest wOBA in away games, and on Wednesday they’re in St. Petersburg to face and the in pitcher-friendly Tropicana Field. Martinez’s strikeouts are down, but his velocity matches career levels. However, his pitch mix is different, as his new team is trying to find the ideal distribution. They excel in this area, so look for Martinez’s strikeouts to pick up.

So far, the cool temperatures have masked the new dimension at Kauffman Stadium, but the mercury is rising and the offense should follow. The take on and the . The veteran right-hander generally does a good job keeping the ball in the yard, but he only has seven strikeouts and a whopping 11 walks in 18 innings. The conditions on Wednesday significantly favor hitters, with , and enjoying the platoon edge and set to take advantage.

The host the at Progressive Field. Injuries have forced the Astros to hand the ball to , seemingly favoring Guardians hitters. In his first start with Houston, Lambert yielded four runs in five frames, but he punched out eight and threw harder than he did in his time with the . In addition, the wind is forecast to blow in, setting a trap for Cleveland hitters. is always an automatic start, but the rest of the lineup could be in for a frustrating evening.

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